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巢國祥，博士，揚(yáng)州市疾病預(yù)防控制中心主任醫(yī)師、研究員。揚(yáng)

州市首席食品安全專家。揚(yáng)州大學(xué)碩士研究生導(dǎo)師、東南大學(xué)碩士

研究生導(dǎo)師、徐州醫(yī)科大學(xué)碩士研究生導(dǎo)師。江蘇省預(yù)防醫(yī)學(xué)會微

生物學(xué)學(xué)組常務(wù)委員、衛(wèi)生標(biāo)準(zhǔn)委員會委員。 《International Journal of Food Microbiology》、《Food Control》、 《Journal of Medical Microbiology》、《Foodborne Pathogens and Diease》等 SCI 期刊審稿

專家。

長期從事食品安全及重大突發(fā)事件控制、致病性微生物分子流行

病學(xué)、檢驗(yàn)方法研究。在單核細(xì)胞增生李斯特氏菌流行與控制、副溶

血性弧菌致病克隆的起源及溯源研究、新型金黃色葡萄球菌超級耐藥

菌溯源、沙門氏菌新克隆致病及耐藥機(jī)制方面研究取得重要進(jìn)展與突

破。發(fā)現(xiàn) 1996 年以來導(dǎo)致世界范圍大流行的副溶性弧菌高致病克隆

最初起源，研究成果被美國 FDA 確認(rèn)為國際重大發(fā)現(xiàn)。2006 年以來

以第一作者發(fā)表相關(guān)SCI 收錄論文16 篇。2006 年以來先后參與及主

持國家級自然科學(xué)基金、江蘇省自然基金、省衛(wèi)生廳科技立項(xiàng)及揚(yáng)州

市社會發(fā)展科研項(xiàng)目科研項(xiàng)目，參加“十二 五”國家科技支撐課題。

先后主持與參與 4 項(xiàng)國家食品安全標(biāo)準(zhǔn)微生物檢驗(yàn)標(biāo)準(zhǔn)及青奧會食

品安全微生物相關(guān)標(biāo)準(zhǔn)的修定與審核。

所參加的研究項(xiàng)目與課題獲得2017 年國家科學(xué)技術(shù)進(jìn)步獎二等

獎、2014 省衛(wèi)生新技術(shù)引進(jìn)獎二等獎、2013 年度教育部科學(xué)技術(shù)獎

一等獎、2012 年江蘇省政府科學(xué)技術(shù)獎二等獎、2011 年揚(yáng)州市科學(xué)

技術(shù)獎二等獎等獎項(xiàng)。

部分第一作者SCI 收錄論文

1.     Yongzhong Cao, Yongxiu Shen, Lingling Cheng, Xiaorong Zhang, Chao Wang, Yan Wang, Xiaohui Zhou*, Guoxiang Chao*, Yantao Wu*. Combination of multilocus sequence typing and pulsed-field gel electrophoresis reveals an association of molecular clonality with the emergence of extensive-drug resistance (XDR) in Salmonella.Microbiological Research 207 (2018) 170–176.

2.     Guoxiang Chao, Chao Wang, Tianqi Wu, Xiaorong Zhang, Jianhao Chen, Xiaoxing Qi, Yongzhong Cao, Yantao Wu*, Xinan Jiao*. Molecular epidemiology and antibiotic resistance phenotypes and genotypes of salmonellae from food supply chains in China. Food Control 77 (2017) 32-40.

3. Yongzhong Cao, Jie Wang, Ran Wang, Xiaorong Zhang, Guoxiang Chao*, and Yantao*. Prevalence and characterization of resistance genes with genetic clones among Staphylococcus aureus isolates obtained from various sources in China. Journal of Medical Microbiology, 2016; 65: 569-571.

4.     Guoxiang Chao*, Guangyu Bao, Wenguang Yan, Yan Wang, Xiaorong Zhang, Liping Zhou, Yantao Wu*. Prevalence and diversity of enterotoxin genes with genetic background of

Staphylococcus aureus strains from different origins in China. International Journal of Food Microbiology. 2015, 211:142-147.

5.     Chao Guoxiang, Bao Guangyu, Jiao Xinan. Molecular epidemiological characteristics and clonal genetic diversity of Staphylococcus aureus with different origins in China. Foodborne Pathog Dis 2014;7:503～510.

6.     Chao Guoxiang, Xiaoping Zhang, Xiaorong Zhang, Yao Huang, Lan Xu,Liping Zhou, Weixia Yang, Yuan Jiang, Feng Xue, Yantao Wu*. Phenotypic and genotypic characterization of methicillin-resistant Staphylococcus aureus (MRSA) and methicillin-susceptible Staphylococcus aureus (MSSA) from different sources in China. Foodborne Pathog Dis 2013;10: 214～221.

7.     Chao Guoxiang*, Fang Wang, Xiaohui Zhou, Xinan Jiao*, Jinlin Huang, Zhiming Pan, Liping Zhou, Xiaoqin Qian. Origin of Vibrio Parahaemolyticus O3:K6 pandemic clone.

International Journal of Food Microbiology 2011;145:259-263

8.     Chao Guoxiang, Xinan Jiao*, Xiaohui Zhou, Fang Wang, Zhenquan Yang, Jinlin Huang, Zhiming Pan, Liping Zhou, Xiaoqin Qian. Distribution of genes encoding 4 pathogenicity islands (VPaIs), T6SS, biofilm, and type Ⅰ pilus in food and clinical strains of Vibrio parahaemolyticus in China. Foodborne Pathog Dis 2010;7(6):649-658.

9.     Chao Guoxiang, Xinan Jiao*, Xiaohui Zhou, Zhenquan Yang, Jinlin Huang, Zhiming Pan,Liping Zhou, Xiaoqin Qian. Serodiversity, pandemic O3:K6 clone, molecular typing, and antibiotic susceptibility of foodborne and clinical Vibrio parahaemolyticus isolates in Jiangsu, China. Foodborne Pathog Dis 2009;8:1021-1028.

10.  Chao Guoxiang, Xinan Jiao*, Xiaohui Zhou, Zhenquan Yang, Zhiming Pan, Jinlin Huang, Lipin Zhou, Xiaoqin Qian. Systematic Functional Pandemic-strain-specific Genes, Three